diff --git a/jedi/evaluate/compiled/__init__.py b/jedi/evaluate/compiled/__init__.py
index d03d66e0..66a058a7 100644
--- a/jedi/evaluate/compiled/__init__.py
+++ b/jedi/evaluate/compiled/__init__.py
@@ -322,7 +322,14 @@ def load_module(path, name):
         sys_path.insert(0, p)
 
     temp, sys.path = sys.path, sys_path
-    __import__(dotted_path)
+    try:
+        __import__(dotted_path)
+    except RuntimeError:
+        if 'PySide' in dotted_path or 'PyQt' in dotted_path:
+            # RuntimeError: the PyQt4.QtCore and PyQt5.QtCore modules both wrap
+            # the QObject class.
+            # See https://github.com/davidhalter/jedi/pull/483
+            return None
     # Just access the cache after import, because of #59 as well as the very
     # complicated import structure of Python.
     module = sys.modules[dotted_path]
diff --git a/jedi/evaluate/imports.py b/jedi/evaluate/imports.py
index a1ceb330..0c77494e 100644
--- a/jedi/evaluate/imports.py
+++ b/jedi/evaluate/imports.py
@@ -190,6 +190,9 @@ class ImportWrapper(pr.Base):
                     analysis.add(self._evaluator, 'import-error', e.name_part)
                     return []
 
+                if module is None:
+                    return []
+
                 if self.import_stmt.is_nested() and not self.nested_resolve:
                     scopes = [NestedImportModule(module, self.import_stmt)]
                 else: