diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 188d3e34..e306eb50 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -7,8 +7,8 @@ jobs:
     strategy:
       matrix:
         os: [ubuntu-20.04, windows-2019]
-        python-version: [3.9, 3.8, 3.7, 3.6]
-        environment: ['3.8', '3.9', '3.7', '3.6', 'interpreter']
+        python-version: ["3.10", "3.9", "3.8", "3.7", "3.6"]
+        environment: ['3.8', '3.10', '3.9', '3.7', '3.6', 'interpreter']
     steps:
       - name: Checkout code
         uses: actions/checkout@v2
diff --git a/CHANGELOG.rst b/CHANGELOG.rst
index 3cc23d43..52a6e792 100644
--- a/CHANGELOG.rst
+++ b/CHANGELOG.rst
@@ -6,7 +6,11 @@ Changelog
 Unreleased
 ++++++++++
 
+0.18.1 (2021-11-17)
++++++++++++++++++++
+
 - Implict namespaces are now a separate types in ``Name().type``
+- Python 3.10 support
 
 0.18.0 (2020-12-25)
 +++++++++++++++++++
diff --git a/jedi/api/classes.py b/jedi/api/classes.py
index fba9b5ad..ee741c33 100644
--- a/jedi/api/classes.py
+++ b/jedi/api/classes.py
@@ -27,7 +27,7 @@ from jedi.inference.compiled.mixed import MixedName
 from jedi.inference.names import ImportName, SubModuleName
 from jedi.inference.gradual.stub_value import StubModuleValue
 from jedi.inference.gradual.conversion import convert_names, convert_values
-from jedi.inference.base_value import ValueSet
+from jedi.inference.base_value import ValueSet, HasNoContext
 from jedi.api.keywords import KeywordName
 from jedi.api import completion_cache
 from jedi.api.helpers import filter_follow_imports
@@ -37,13 +37,17 @@ def _sort_names_by_start_pos(names):
     return sorted(names, key=lambda s: s.start_pos or (0, 0))
 
 
-def defined_names(inference_state, context):
+def defined_names(inference_state, value):
     """
     List sub-definitions (e.g., methods in class).
 
     :type scope: Scope
     :rtype: list of Name
     """
+    try:
+        context = value.as_context()
+    except HasNoContext:
+        return []
     filter = next(context.get_filters())
     names = [name for name in filter.values()]
     return [Name(inference_state, n) for n in _sort_names_by_start_pos(names)]
@@ -759,7 +763,7 @@ class Name(BaseName):
         """
         defs = self._name.infer()
         return sorted(
-            unite(defined_names(self._inference_state, d.as_context()) for d in defs),
+            unite(defined_names(self._inference_state, d) for d in defs),
             key=lambda s: s._name.start_pos or (0, 0)
         )
 
diff --git a/jedi/api/completion.py b/jedi/api/completion.py
index a2ac4d04..342f7506 100644
--- a/jedi/api/completion.py
+++ b/jedi/api/completion.py
@@ -195,7 +195,6 @@ class Completion:
         - In args: */**: no completion
         - In params (also lambda): no completion before =
         """
-
         grammar = self._inference_state.grammar
         self.stack = stack = None
         self._position = (
@@ -278,6 +277,10 @@ class Completion:
                 )
             elif nonterminals[-1] in ('trailer', 'dotted_name') and nodes[-1] == '.':
                 dot = self._module_node.get_leaf_for_position(self._position)
+                if dot.type == "endmarker":
+                    # This is a bit of a weird edge case, maybe we can somehow
+                    # generalize this.
+                    dot = leaf.get_previous_leaf()
                 cached_name, n = self._complete_trailer(dot.get_previous_leaf())
                 completion_names += n
             elif self._is_parameter_completion():
diff --git a/jedi/api/environment.py b/jedi/api/environment.py
index 3f1f238f..aea96c47 100644
--- a/jedi/api/environment.py
+++ b/jedi/api/environment.py
@@ -17,7 +17,7 @@ import parso
 
 _VersionInfo = namedtuple('VersionInfo', 'major minor micro')
 
-_SUPPORTED_PYTHONS = ['3.9', '3.8', '3.7', '3.6']
+_SUPPORTED_PYTHONS = ['3.10', '3.9', '3.8', '3.7', '3.6']
 _SAFE_PATHS = ['/usr/bin', '/usr/local/bin']
 _CONDA_VAR = 'CONDA_PREFIX'
 _CURRENT_VERSION = '%s.%s' % (sys.version_info.major, sys.version_info.minor)
diff --git a/jedi/inference/base_value.py b/jedi/inference/base_value.py
index e51e063c..31b72937 100644
--- a/jedi/inference/base_value.py
+++ b/jedi/inference/base_value.py
@@ -22,6 +22,10 @@ from jedi.cache import memoize_method
 sentinel = object()
 
 
+class HasNoContext(Exception):
+    pass
+
+
 class HelperValueMixin:
     def get_root_context(self):
         value = self
@@ -261,7 +265,7 @@ class Value(HelperValueMixin):
         return self.parent_context.is_stub()
 
     def _as_context(self):
-        raise NotImplementedError('Not all values need to be converted to contexts: %s', self)
+        raise HasNoContext
 
     @property
     def name(self):
diff --git a/jedi/inference/names.py b/jedi/inference/names.py
index f90f9749..f446deb9 100644
--- a/jedi/inference/names.py
+++ b/jedi/inference/names.py
@@ -341,6 +341,12 @@ class TreeNameDefinition(AbstractTreeName):
     def py__doc__(self):
         api_type = self.api_type
         if api_type in ('function', 'class', 'property'):
+            if self.parent_context.get_root_context().is_stub():
+                from jedi.inference.gradual.conversion import convert_names
+                names = convert_names([self], prefer_stub_to_compiled=False)
+                if self not in names:
+                    return _merge_name_docs(names)
+
             # Make sure the names are not TreeNameDefinitions anymore.
             return clean_scope_docstring(self.tree_name.get_definition())
 
@@ -408,6 +414,9 @@ class ParamNameInterface(_ParamMixin):
             return 2
         return 0
 
+    def infer_default(self):
+        return NO_VALUES
+
 
 class BaseTreeParamName(ParamNameInterface, AbstractTreeName):
     annotation_node = None
diff --git a/jedi/inference/value/iterable.py b/jedi/inference/value/iterable.py
index 2f970fe8..7cc37173 100644
--- a/jedi/inference/value/iterable.py
+++ b/jedi/inference/value/iterable.py
@@ -342,6 +342,8 @@ class SequenceLiteralValue(Sequence):
         else:
             with reraise_getitem_errors(TypeError, KeyError, IndexError):
                 node = self.get_tree_entries()[index]
+            if node == ':' or node.type == 'subscript':
+                return NO_VALUES
             return self._defining_context.infer_node(node)
 
     def py__iter__(self, contextualized_node=None):
@@ -407,16 +409,6 @@ class SequenceLiteralValue(Sequence):
             else:
                 return [array_node]
 
-    def exact_key_items(self):
-        """
-        Returns a generator of tuples like dict.items(), where the key is
-        resolved (as a string) and the values are still lazy values.
-        """
-        for key_node, value in self.get_tree_entries():
-            for key in self._defining_context.infer_node(key_node):
-                if is_string(key):
-                    yield key.get_safe_value(), LazyTreeValue(self._defining_context, value)
-
     def __repr__(self):
         return "<%s of %s>" % (self.__class__.__name__, self.atom)
 
@@ -472,6 +464,16 @@ class DictLiteralValue(_DictMixin, SequenceLiteralValue, _DictKeyMixin):
 
         return ValueSet([FakeList(self.inference_state, lazy_values)])
 
+    def exact_key_items(self):
+        """
+        Returns a generator of tuples like dict.items(), where the key is
+        resolved (as a string) and the values are still lazy values.
+        """
+        for key_node, value in self.get_tree_entries():
+            for key in self._defining_context.infer_node(key_node):
+                if is_string(key):
+                    yield key.get_safe_value(), LazyTreeValue(self._defining_context, value)
+
     def _dict_values(self):
         return ValueSet.from_sets(
             self._defining_context.infer_node(v)
diff --git a/jedi/plugins/pytest.py b/jedi/plugins/pytest.py
index 0e196c72..c78bdb4f 100644
--- a/jedi/plugins/pytest.py
+++ b/jedi/plugins/pytest.py
@@ -31,7 +31,15 @@ def execute(callback):
 def infer_anonymous_param(func):
     def get_returns(value):
         if value.tree_node.annotation is not None:
-            return value.execute_with_values()
+            result = value.execute_with_values()
+            if any(v.name.get_qualified_names(include_module_names=True)
+                   == ('typing', 'Generator')
+                   for v in result):
+                return ValueSet.from_sets(
+                    v.py__getattribute__('__next__').execute_annotation()
+                    for v in result
+                )
+            return result
 
         # In pytest we need to differentiate between generators and normal
         # returns.
diff --git a/setup.py b/setup.py
index 1f660a4d..e20d14c2 100755
--- a/setup.py
+++ b/setup.py
@@ -35,7 +35,7 @@ setup(name='jedi',
       install_requires=['parso>=0.8.0,<0.9.0'],
       extras_require={
           'testing': [
-              'pytest<6.0.0',
+              'pytest<7.0.0',
               # docopt for sith doctests
               'docopt',
               # coloroma for colored debug output
@@ -61,6 +61,7 @@ setup(name='jedi',
           'Programming Language :: Python :: 3.7',
           'Programming Language :: Python :: 3.8',
           'Programming Language :: Python :: 3.9',
+          'Programming Language :: Python :: 3.10',
           'Topic :: Software Development :: Libraries :: Python Modules',
           'Topic :: Text Editors :: Integrated Development Environments (IDE)',
           'Topic :: Utilities',
diff --git a/test/completion/arrays.py b/test/completion/arrays.py
index 59b8f2fe..21437bce 100644
--- a/test/completion/arrays.py
+++ b/test/completion/arrays.py
@@ -44,6 +44,8 @@ b[int():]
 
 #? list()
 b[:]
+#? int()
+b[:, :-1]
 
 #? 3
 b[:]
@@ -67,6 +69,20 @@ class _StrangeSlice():
 #? slice()
 _StrangeSlice()[1:2]
 
+for x in b[:]:
+    #? int()
+    x
+
+for x in b[:, :-1]:
+    #?
+    x
+
+class Foo:
+    def __getitem__(self, item):
+        return item
+
+#?
+Foo()[:, :-1][0]
 
 # -----------------
 # iterable multiplication
diff --git a/test/completion/docstring.py b/test/completion/docstring.py
index 5160610f..b2d02239 100644
--- a/test/completion/docstring.py
+++ b/test/completion/docstring.py
@@ -284,6 +284,13 @@ def doctest_with_space():
         import_issu
     """
 
+def doctest_issue_github_1748():
+    """From GitHub #1748
+    #? 10 []
+    This. Al
+    """
+    pass
+
 
 def docstring_rst_identifiers():
     """
diff --git a/test/completion/pytest.py b/test/completion/pytest.py
index 3c648c6c..a900dcda 100644
--- a/test/completion/pytest.py
+++ b/test/completion/pytest.py
@@ -1,3 +1,5 @@
+from typing import Generator
+
 import pytest
 from pytest import fixture
 
@@ -169,3 +171,15 @@ def test_inheritance_fixture(inheritance_fixture, caplog):
 @pytest.fixture
 def caplog(caplog):
     yield caplog
+
+# -----------------
+# Generator with annotation
+# -----------------
+
+@pytest.fixture
+def with_annot() -> Generator[float, None, None]:
+    pass
+
+def test_with_annot(inheritance_fixture, with_annot):
+    #? float()
+    with_annot
diff --git a/test/test_api/test_completion.py b/test/test_api/test_completion.py
index 8e5ec3b2..de46223e 100644
--- a/test/test_api/test_completion.py
+++ b/test/test_api/test_completion.py
@@ -457,3 +457,7 @@ def test_module_completions(Script, module):
         # Just make sure that there are no errors
         c.type
         c.docstring()
+
+
+def test_whitespace_at_end_after_dot(Script):
+    assert 'strip' in [c.name for c in Script('str. ').complete()]
diff --git a/test/test_api/test_documentation.py b/test/test_api/test_documentation.py
index b86c68fc..4c09d612 100644
--- a/test/test_api/test_documentation.py
+++ b/test/test_api/test_documentation.py
@@ -37,6 +37,17 @@ def test_operator_doc(Script):
     assert len(d.docstring()) > 100
 
 
+@pytest.mark.parametrize(
+    'code, help_part', [
+        ('str', 'Create a new string object'),
+        ('str.strip', 'Return a copy of the string'),
+    ]
+)
+def test_stdlib_doc(Script, code, help_part):
+    h, = Script(code).help()
+    assert help_part in h.docstring(raw=True)
+
+
 def test_lambda(Script):
     d, = Script('lambda x: x').help(column=0)
     assert d.type == 'keyword'
diff --git a/test/test_api/test_interpreter.py b/test/test_api/test_interpreter.py
index e6232e05..131ec6c1 100644
--- a/test/test_api/test_interpreter.py
+++ b/test/test_api/test_interpreter.py
@@ -732,3 +732,10 @@ def test_complete_not_findable_class_source():
 
     assert "ta" in [c.name for c in completions]
     assert "ta1" in [c.name for c in completions]
+
+
+def test_param_infer_default():
+    abs_sig, = jedi.Interpreter('abs(', [{'abs': abs}]).get_signatures()
+    param, = abs_sig.params
+    assert param.name == 'x'
+    assert param.infer_default() == []
diff --git a/test/test_api/test_names.py b/test/test_api/test_names.py
index d43a29bb..287a301e 100644
--- a/test/test_api/test_names.py
+++ b/test/test_api/test_names.py
@@ -189,3 +189,9 @@ def test_no_error(get_names):
 def test_is_side_effect(get_names, code, index, is_side_effect):
     names = get_names(code, references=True, all_scopes=True)
     assert names[index].is_side_effect() == is_side_effect
+
+
+def test_no_defined_names(get_names):
+    definition, = get_names("x = (1, 2)")
+
+    assert not definition.defined_names()
diff --git a/test/test_utils.py b/test/test_utils.py
index c6198401..0dcf80db 100644
--- a/test/test_utils.py
+++ b/test/test_utils.py
@@ -85,7 +85,7 @@ class TestSetupReadline(unittest.TestCase):
         }
         # There are quite a few differences, because both Windows and Linux
         # (posix and nt) librariesare included.
-        assert len(difference) < 15
+        assert len(difference) < 30
 
     def test_local_import(self):
         s = 'import test.test_utils'