diff --git a/stdlib/asyncio/protocols.pyi b/stdlib/asyncio/protocols.pyi
index caae5d865..7b5169702 100644
--- a/stdlib/asyncio/protocols.pyi
+++ b/stdlib/asyncio/protocols.pyi
@@ -1,5 +1,6 @@
 import sys
 from asyncio import transports
+from typing import Any
 
 if sys.version_info >= (3, 7):
     __all__ = ("BaseProtocol", "Protocol", "DatagramProtocol", "SubprocessProtocol", "BufferedProtocol")
@@ -24,7 +25,11 @@ if sys.version_info >= (3, 7):
 
 class DatagramProtocol(BaseProtocol):
     def connection_made(self, transport: transports.DatagramTransport) -> None: ...  # type: ignore[override]
-    def datagram_received(self, data: bytes, addr: tuple[str, int]) -> None: ...
+    # addr can be a tuple[int, int] for some unusual protocols like socket.AF_NETLINK.
+    # Use tuple[str | Any, int] to not cause typechecking issues on most usual cases.
+    # This could be improved by using tuple[AnyOf[str, int], int] if the AnyOf feature is accepted.
+    # See https://github.com/python/typing/issues/566
+    def datagram_received(self, data: bytes, addr: tuple[str | Any, int]) -> None: ...
     def error_received(self, exc: Exception) -> None: ...
 
 class SubprocessProtocol(BaseProtocol):