diff --git a/stubs/protobuf/@tests/stubtest_allowlist.txt b/stubs/protobuf/@tests/stubtest_allowlist.txt
index f688f9a48..f658877f9 100644
--- a/stubs/protobuf/@tests/stubtest_allowlist.txt
+++ b/stubs/protobuf/@tests/stubtest_allowlist.txt
@@ -23,3 +23,12 @@ google.protobuf.text_format.MessageToBytes
 # Stubbed as static method, but actually exists as a property that's
 # a function. Typeshed's typing is more useful
 google.protobuf.service.Service.GetDescriptor
+
+# These are deliberately omitted in the stub
+# due to the fact that these classes have conflicting signatures for __init__/__new__.
+# The classes also can't be constructed directly anyway,
+# so the signatures of their constructors are somewhat irrelevant.
+google.protobuf.descriptor.Descriptor.__init__
+google.protobuf.descriptor.Descriptor.__new__
+google.protobuf.descriptor.ServiceDescriptor.__init__
+google.protobuf.descriptor.ServiceDescriptor.__new__
diff --git a/stubs/protobuf/google/protobuf/descriptor.pyi b/stubs/protobuf/google/protobuf/descriptor.pyi
index 690c312b8..904f74c01 100644
--- a/stubs/protobuf/google/protobuf/descriptor.pyi
+++ b/stubs/protobuf/google/protobuf/descriptor.pyi
@@ -45,27 +45,6 @@ class _NestedDescriptorBase(DescriptorBase):
     def CopyToProto(self, proto): ...
 
 class Descriptor(_NestedDescriptorBase):
-    def __new__(
-        cls,
-        name=...,
-        full_name=...,
-        filename=...,
-        containing_type=...,
-        fields=...,
-        nested_types=...,
-        enum_types=...,
-        extensions=...,
-        options=...,
-        serialized_options=...,
-        is_extendable=...,
-        extension_ranges=...,
-        oneofs=...,
-        file=...,
-        serialized_start=...,
-        serialized_end=...,
-        syntax=...,
-        create_key=...,
-    ): ...
     fields: Any
     fields_by_number: Any
     fields_by_name: Any
@@ -81,27 +60,6 @@ class Descriptor(_NestedDescriptorBase):
     oneofs: Any
     oneofs_by_name: Any
     syntax: Any
-    def __init__(
-        self,
-        name,
-        full_name,
-        filename,
-        containing_type,
-        fields,
-        nested_types,
-        enum_types,
-        extensions,
-        options=...,
-        serialized_options=...,
-        is_extendable=...,
-        extension_ranges=...,
-        oneofs=...,
-        file=...,
-        serialized_start=...,
-        serialized_end=...,
-        syntax=...,
-        create_key=...,
-    ) -> None: ...
     def EnumValueName(self, enum, value): ...
     def CopyToProto(self, proto): ...
     def GetOptions(self) -> MessageOptions: ...
@@ -266,35 +224,9 @@ class OneofDescriptor:
     def GetOptions(self) -> OneofOptions: ...
 
 class ServiceDescriptor(_NestedDescriptorBase):
-    def __new__(
-        cls,
-        name=...,
-        full_name=...,
-        index=...,
-        methods=...,
-        options=...,
-        serialized_options=...,
-        file=...,
-        serialized_start=...,
-        serialized_end=...,
-        create_key=...,
-    ): ...
     index: Any
     methods: Any
     methods_by_name: Any
-    def __init__(
-        self,
-        name,
-        full_name,
-        index,
-        methods,
-        options=...,
-        serialized_options=...,
-        file=...,
-        serialized_start=...,
-        serialized_end=...,
-        create_key=...,
-    ) -> None: ...
     def FindMethodByName(self, name): ...
     def CopyToProto(self, proto): ...
     def GetOptions(self) -> ServiceOptions: ...