diff --git a/scripts/generate_proto_stubs.sh b/scripts/generate_proto_stubs.sh
index 89edfc8b8..1bb7a8c6a 100755
--- a/scripts/generate_proto_stubs.sh
+++ b/scripts/generate_proto_stubs.sh
@@ -11,7 +11,7 @@ set -ex -o pipefail
 # followed by committing the changes to typeshed
 #
 # Update these two variables when rerunning script
-PROTOBUF_VERSION=3.18.1
+PROTOBUF_VERSION=3.19.2
 MYPY_PROTOBUF_VERSION=v3.0.0
 
 if uname -a | grep Darwin; then
@@ -74,4 +74,5 @@ protoc_install/bin/protoc --proto_path="$PYTHON_PROTOBUF_DIR/src" --mypy_out="$R
 isort "$REPO_ROOT/stubs/protobuf"
 black "$REPO_ROOT/stubs/protobuf"
 
-sed -i="" "s/mypy-protobuf [^\"]*/mypy-protobuf ${MYPY_PROTOBUF_VERSION}/" "$REPO_ROOT/stubs/protobuf/METADATA.toml"
+sed -i "" "s/mypy-protobuf [^\"]*/mypy-protobuf ${MYPY_PROTOBUF_VERSION}/" "$REPO_ROOT/stubs/protobuf/METADATA.toml"
+sed -i "" "s/version = .*$/version = \"$(echo ${PROTOBUF_VERSION} | cut -d. -f1-2)\.\*\"/" "$REPO_ROOT/stubs/protobuf/METADATA.toml"
diff --git a/stubs/protobuf/@tests/stubtest_allowlist.txt b/stubs/protobuf/@tests/stubtest_allowlist.txt
index 2c5e07c85..5c52da428 100644
--- a/stubs/protobuf/@tests/stubtest_allowlist.txt
+++ b/stubs/protobuf/@tests/stubtest_allowlist.txt
@@ -99,13 +99,8 @@ google.protobuf.duration_pb2.Duration.__init__
 google.protobuf.empty_pb2.Empty.__init__
 google.protobuf.field_mask_pb2.FieldMask.__init__
 google.protobuf.internal.containers.BaseContainer.sort
-google.protobuf.internal.containers.Mapping
 google.protobuf.internal.containers.MessageMap.__init__
 google.protobuf.internal.containers.MessageMap.get
-google.protobuf.internal.containers.MutableMapping.__delitem__
-google.protobuf.internal.containers.MutableMapping.__setitem__
-google.protobuf.internal.containers.MutableMapping.pop
-google.protobuf.internal.containers.MutableMapping.setdefault
 google.protobuf.internal.containers.RepeatedCompositeFieldContainer.__init__
 google.protobuf.internal.containers.RepeatedScalarFieldContainer.__init__
 google.protobuf.internal.containers.ScalarMap.__init__
@@ -123,7 +118,6 @@ google.protobuf.internal.well_known_types.Error
 google.protobuf.internal.well_known_types.ParseError
 google.protobuf.message.Message.DESCRIPTOR
 google.protobuf.message.Message.Extensions
-google.protobuf.message.Message.FromString
 google.protobuf.message.Message.SerializePartialToString
 google.protobuf.message.Message.SerializeToString
 google.protobuf.message.Message.__init__
diff --git a/stubs/protobuf/METADATA.toml b/stubs/protobuf/METADATA.toml
index c551073ba..cd11ebcd1 100644
--- a/stubs/protobuf/METADATA.toml
+++ b/stubs/protobuf/METADATA.toml
@@ -1,4 +1,4 @@
-version = "3.18.*"
+version = "3.19.*"
 python2 = true
 requires = ["types-futures"]
 extra_description = "Generated with aid from mypy-protobuf v3.0.0"
diff --git a/stubs/protobuf/google/protobuf/internal/containers.pyi b/stubs/protobuf/google/protobuf/internal/containers.pyi
index cef517ec2..170f34cb5 100644
--- a/stubs/protobuf/google/protobuf/internal/containers.pyi
+++ b/stubs/protobuf/google/protobuf/internal/containers.pyi
@@ -1,18 +1,5 @@
-from typing import (
-    Any,
-    Callable,
-    Iterable,
-    Iterator,
-    List,
-    Mapping as Mapping,
-    MutableMapping as MutableMapping,
-    Optional,
-    Sequence,
-    Text,
-    TypeVar,
-    Union,
-    overload,
-)
+from collections.abc import MutableMapping
+from typing import Any, Callable, Iterable, Iterator, List, Optional, Sequence, Text, TypeVar, Union, overload
 from typing_extensions import SupportsIndex
 
 from google.protobuf.descriptor import Descriptor
diff --git a/stubs/protobuf/google/protobuf/message.pyi b/stubs/protobuf/google/protobuf/message.pyi
index 8d63932e1..9e23bae8f 100644
--- a/stubs/protobuf/google/protobuf/message.pyi
+++ b/stubs/protobuf/google/protobuf/message.pyi
@@ -1,5 +1,4 @@
-import sys
-from typing import Any, ByteString, Sequence, Tuple, Type, TypeVar, Union
+from typing import Any, Sequence, Tuple, Type, TypeVar
 
 from .descriptor import Descriptor, FieldDescriptor
 from .internal.extension_dict import _ExtensionDict, _ExtensionFieldDescriptor
@@ -10,11 +9,6 @@ class EncodeError(Error): ...
 
 _M = TypeVar("_M", bound=Message)  # message type (of self)
 
-if sys.version_info >= (3, 0):
-    _Serialized = ByteString
-else:
-    _Serialized = Union[bytes, buffer, unicode]
-
 class Message:
     DESCRIPTOR: Descriptor
     def __deepcopy__(self, memo=...): ...
@@ -25,8 +19,8 @@ class Message:
     def Clear(self) -> None: ...
     def SetInParent(self) -> None: ...
     def IsInitialized(self) -> bool: ...
-    def MergeFromString(self, serialized: _Serialized) -> int: ...
-    def ParseFromString(self, serialized: _Serialized) -> int: ...
+    def MergeFromString(self, serialized: bytes) -> int: ...
+    def ParseFromString(self, serialized: bytes) -> int: ...
     def SerializeToString(self, deterministic: bool = ...) -> bytes: ...
     def SerializePartialToString(self, deterministic: bool = ...) -> bytes: ...
     def ListFields(self) -> Sequence[Tuple[FieldDescriptor, Any]]: ...
@@ -34,7 +28,7 @@ class Message:
     def ClearExtension(self: _M, extension_handle: _ExtensionFieldDescriptor[_M, Any]) -> None: ...
     def ByteSize(self) -> int: ...
     @classmethod
-    def FromString(cls: Type[_M], s: _Serialized) -> _M: ...
+    def FromString(cls: Type[_M], s: bytes) -> _M: ...
     @property
     def Extensions(self: _M) -> _ExtensionDict[_M]: ...
     # Intentionally left out typing on these three methods, because they are
diff --git a/stubs/protobuf/google/protobuf/struct_pb2.pyi b/stubs/protobuf/google/protobuf/struct_pb2.pyi
index 54e8df72a..ade8d5ad0 100644
--- a/stubs/protobuf/google/protobuf/struct_pb2.pyi
+++ b/stubs/protobuf/google/protobuf/struct_pb2.pyi
@@ -75,8 +75,8 @@ global___Struct = Struct
 class Value(google.protobuf.message.Message):
     """`Value` represents a dynamically typed value which can be either
     null, a number, a string, a boolean, a recursive struct value, or a
-    list of values. A producer of value is expected to set one of that
-    variants, absence of any variant indicates an error.
+    list of values. A producer of value is expected to set one of these
+    variants. Absence of any variant indicates an error.
 
     The JSON representation for `Value` is JSON value.
     """
diff --git a/stubs/protobuf/google/protobuf/text_format.pyi b/stubs/protobuf/google/protobuf/text_format.pyi
index eafb77a63..52f866047 100644
--- a/stubs/protobuf/google/protobuf/text_format.pyi
+++ b/stubs/protobuf/google/protobuf/text_format.pyi
@@ -1,4 +1,3 @@
-import sys
 from _typeshed import SupportsWrite
 from typing import Any, Callable, Iterable, Optional, Text, Tuple, TypeVar, Union
 
@@ -6,9 +5,6 @@ from .descriptor import FieldDescriptor
 from .descriptor_pool import DescriptorPool
 from .message import Message
 
-if sys.version_info < (3, 0):
-    long = int
-
 _M = TypeVar("_M", bound=Message)  # message type (of self)
 
 class Error(Exception): ...